Search results for "Food contact"

showing 10 items of 15 documents

Use of reliable bioassays to detect potential hazard of food contact materials extracts to ensure quality, safety and innovation of paperboards

2015

International audience; Food contact materials (FCM) represent a major economic issue and also an important field of innovation for packaging industries. Food packaging production must currently meet manufacturing good practices, safety for human health and thus be in compliance with the article 3 of the European Regulation 1935/2004: “Material and articles in contact with food do not transfer substances in amounts which could endanger human health…”.

0303 health sciencesFood contact materials9. Industry and infrastructureGeneral Medicine[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chainToxicologyHazard03 medical and health sciences0302 clinical medicine[SDV.TOX.TCA] Life Sciences [q-bio]/Toxicology/Toxicology and food chainPackagingFoodFood contact materialsEnvironmental healthQuality safetyEnvironmental science030217 neurology & neurosurgery030304 developmental biology
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Recent European Food Safety Authority toxicological evaluations of major phthalates used in food contact materials

2009

During the 1980s and 1990s, and at the EU level, the Scientific Committee for Food evaluated a number of phthalates that were being used, or were requested for use, as additives in plastics. At this time, peroxisome proliferation was considered as the pivotal effect on which toxicological evaluation of these chemicals was based. At the end of 1990s, a general consensus has been agreed that rodents are highly sensitive to the phenomenon of peroxisome proliferation and that this particular effect should not be used for human risk assessment. Consequently in 2004, it was requested from the newly created European Food Safety Authority to perform a new evaluation of the mainly used phthalates on…

Food contact materialsEndpoint DeterminationPhthalic AcidsPeroxisome ProliferationRisk AssessmentToxicologySpecies SpecificityDiethylhexyl PhthalateEnvironmental healthAnimalsHumansFood contactbusiness.industryFood PackagingLegislation FoodFood safetyDibutyl PhthalateHighly sensitiveEuropeFood packagingBusinessSafetyRisk assessmentEnvironmental MonitoringFood ScienceBiotechnologyMolecular Nutrition & Food Research
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Determination of 60 Migrant Substances in Plastic Food Contact Materials by Vortex-Assisted Liquid-Liquid Extraction and GC-Q-Orbitrap HRMS

2021

A GC-HRMS analytical method for the determination of 60 migrant substances, including aldehydes, ketones, phthalates and other plasticizers, phenol derivatives, acrylates, and methacrylates, in plastic food contact materials (FCM) has been developed and validated. The proposed method includes migration tests, according to Commission Regulation (EU) 10/2011, using four food simulants (A, B, C, and D1), followed by vortex-assisted liquid–liquid extraction (VA-LLE) and GC-Q-Orbitrap HRMS analysis in selected ion monitoring (SIM) mode, with a resolving power of 30,000 FWHM and a mass accuracy ≤5 ppm. The method was validated, showing satisfactory linearity (R2 ≥ 0.98 from 40 to 400 …

gas chromatographyLiquid-Liquid ExtractionOrganic ChemistryFood PackagingPharmaceutical ScienceFood Contaminationfood contact materialsArticleMass Spectrometrymigration testAnalytical ChemistryQD241-441food simulantsPlasticizersChemistry (miscellaneous)Drug DiscoveryMolecular Medicinehigh-resolution mass spectrometrytarget analysisPhysical and Theoretical ChemistryPlasticsfood contact materials; food simulants; gas chromatography; high-resolution mass spectrometry; migration test; target analysisMolecules; Volume 26; Issue 24; Pages: 7640
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An overview of nanoparticles role in the improvement of barrier properties of bioplastics for food packaging applications

2017

Abstract Plastics are the most demanding materials for the food packaging industry due to economical and practical reasons such as their low cost, lightness, easy to handle in integrated production lines, and their higher resistance than other materials. Besides containment and information, the packaging should protect foodstuffs from not only contamination but also the loss of food quality. Despite the many advantages, their inherent permeability is perhaps the foremost drawback that could lead to the loss of some food components and, also, to the transference of gases or moisture from the surrounding to the food. Thus, the barrier properties and the wettability are of fundamental importan…

Food contact materialsMaterials sciencebusiness.industryNanoparticleNanotechnology02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnologyFood safety01 natural sciencesBioplastic0104 chemical sciencesFood packagingIntegrated productionFood componentsBiochemical engineering0210 nano-technologybusinessFood quality
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Fostering the antiviral activity of green tea extract for sanitizing purposes through controlled storage conditions

2018

Food-contact surfaces is considered an important vehicle for the indirect transmission of foodborne viral diseases with enteric viruses, especially human norovirus (HuNoV) and hepatitis A virus (HAV). The aim of the present study was to evaluate the antiviral activity of green tea extract (GTE) at room temperature as a function of pH and storage time and to relate it with changes in composition as a consequence of degradation and epimerization reactions in the storage conditions. The obtained results revealed that freshly prepared GTE was very effective in inactivating murine norovirus (MNV) and HAV at neutral and alkaline pH but was ineffective at pH 5.5. Additionally, storage of the solut…

0301 basic medicinevirusesDisinfectantEnteric viruses030106 microbiologyved/biology.organism_classification_rank.speciesGreen tea extractNatural compoundsmedicine.disease_causeMicrobiology03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologymedicineFood scienceInfectivityFood contactChemistryved/biologyCatechin04 agricultural and veterinary sciencesHuman decontamination040401 food scienceFood-contact surfacesNorovirusFood ScienceBiotechnologyMurine norovirusFood Control
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Safety assessment of food-contact paper and board using a battery of short-term toxicity tests: European union BIOSAFEPAPER project.

2005

International audience; An European Union (EU)-funded project QLK1-CT-2001-00930 (BIOSAFEPAPER) involves the development, validation and intercalibration of a short-term battery of toxicological tests for the safety assessment of food-contact paper and board. Dissemination of the results to industry, legislators (e.g. DG Consumer Protection, DG Enterprises, DG Research), standardization bodies such as CEN, and consumers will create an agreed risk evaluation procedure. The project involves pre-normative research in order to establish a set of in-vitro cytotoxicity and genotoxicity tests that will be easily adaptable to food-contact fibre-based materials and have endpoints relevant to consume…

StandardizationHealth Toxicology and MutagenesisToxicologyMice0302 clinical medicineEnvironmental protectionShort term toxicityCells Culturedmedia_commonMammals0303 health sciencesFood PackagingRisk analysis (engineering)extraction proceduresChemistry (miscellaneous)030220 oncology & carcinogenesisSafetyPaperBattery (electricity)CellsFood Contamination[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chainModels BiologicalRisk AssessmentGas Chromatography-Mass Spectrometry03 medical and health sciencesCell Line TumorToxicity TestsAnimalsHumansmedia_common.cataloged_instanceDimethyl Sulfoxidepaper and boardEuropean UnionEuropean union030304 developmental biologyEthanolFood contactMutagenicity Testsbusiness.industryPublic Health Environmental and Occupational HealthProduct testingWaterEnvironmental ExposureGeneral ChemistryConsumer protectionFood safetyCytotoxicity assaysBusinessFood AnalysisFood Science
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Sanitizing food contact surfaces by the use of essential oils

2018

Chemical sanitizers continue to be widely used by the food industry to disinfect food contact surfaces. However, as some chemical disinfectants have been reported to produce unhealthy by-products, alternative and natural compounds need to be investigated. To this end, nine essential oils (EOs) were screened to develop a natural sanitizing solution (SAN) for disinfecting food contact surfaces. Once extracted, their antimicrobial activity and chemical composition were determined. An exploratory multivariate approach was used to investigate the relationships between the chemical and microbiological data sets. Among the tested EOs, Thymbra capitata EO, containing up to 93.31% oxygenated monoter…

Natural sanitizersFood industryContact timeIndustrial and Manufacturing EngineeringFood safetychemistry.chemical_compound0404 agricultural biotechnologyThymbra capitataCarvacrolFood scienceFood contact surfacesFood contactbiologybusiness.industry04 agricultural and veterinary sciencesGeneral ChemistryAntimicrobialFood safetybiology.organism_classification040401 food scienceFoodborne pathogenschemistrySalmonella entericaEssential oilsbusinessFood Science
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Test procedures for obtaining representative extracts suitable for reliable in vitro toxicity assessment of paper and board intended for food contact.

2009

International audience; This paper describes the use of a suite of extraction procedures applicable to the assessment of the in vitro toxicity of paper/board samples intended for food-contact applications. The sample is extracted with ethanol, water, or exposed to modified polyphenylene oxide (Tenax) for fatty, non-fatty and dry food applications, respectively. The water extracts are directly suitable for safety assessment using in vitro bioassays. The ethanol extracts of the paper/board and of the exposed Tenax require pre-concentration to give acceptable sensitivity. This is because the in vitro bioassays can tolerate only a small percentage of added organic solvent before the solvent its…

PaperFood contact materialsHealth Toxicology and MutagenesisSample (material)[ SDV.TOX ] Life Sciences [q-bio]/ToxicologyTenax[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chainIn Vitro TechniquesToxicologyPaper and boardMESH : Gas Chromatography-Mass Spectrometry01 natural sciencesMESH : Food PackagingGas Chromatography-Mass SpectrometryMESH : Toxicity Tests0404 agricultural biotechnologyToxicity TestsBioassayPaperboardMESH : WoodFood contactbusiness.industryTest procedures010401 analytical chemistryExtraction (chemistry)Food PackagingPublic Health Environmental and Occupational HealthLife Sciences04 agricultural and veterinary sciencesGeneral ChemistryGeneral MedicinePulp and paper industryToxicity assessmentWood040401 food science0104 chemical sciencesBiotechnologyMESH : PaperIn vitro testingExtraction proceduresFood contact materialsvisual_artvisual_art.visual_art_mediumEnvironmental sciencebusinessFood Science
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Safety Evaluation of Food contact paper and board using Chemical Tests and in vitro Bioassays-The role of known and unknown substances

2010

International audience; In vitro toxicological tests has have been proposed as an approach to complement the chemical safety assessment of food contact materials, particularly those with a complex or unknown chemical composition such as paper and board. An EU 5th framework program project “BIOSAFEPAPER – Application of bioassays for safety assessment of paper and board for food contact” specially focused on the application of biotests to paper and board. The project included both chemical characterization and toxicological testing of a representative number of paper and board extracts prepared according to the proposed end use (wet, fatty and dry food contact). Among the concerns addressed …

Salmonella typhimuriumFood contact materialsMESH: WoodHealth Toxicology and MutagenesisCytotoxicity[ SDV.TOX ] Life Sciences [q-bio]/Toxicology010501 environmental sciencesmedicine.disease_causeMESH : Gas Chromatography-Mass SpectrometryToxicology01 natural sciencesMESH : Food PackagingMESH : Toxicity Testschemistry.chemical_compoundBioassayMESH: AnimalsMESH : Salmonella typhimuriumChemistryFood PackagingLife Sciences04 agricultural and veterinary sciencesGeneral MedicineWood040401 food scienceMESH : PaperFood packagingMESH : MutagensPackagingFood contact materialsAcrylamideEnvironmental chemistry[SDV.TOX]Life Sciences [q-bio]/ToxicologyToxicityBiological AssayMESH: PaperBioassayPaperMESH: Food PackagingMESH: Cell Line TumorFood Contamination[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chainMESH: Biological Assay0404 agricultural biotechnologyCell Line TumorMESH: MutagensmedicineAnimalsHumansMutagenic compoundsMESH: Toxicity Tests0105 earth and related environmental sciencesMESH : WoodChromatographyMESH: Humansbusiness.industryMESH : Cell Line TumorMESH : HumansPublic Health Environmental and Occupational HealthMESH: Salmonella typhimuriumGeneral ChemistryMESH: Food ContaminationFood safetyMESH: Gas Chromatography-Mass SpectrometryMESH : Food ContaminationMESH : AnimalsMESH : Biological AssaybusinessGenotoxicityMutagensFood ScienceFood contaminant
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Non-target and suspected-target screening for potentially hazardous chemicals in food contact materials: investigation of paper straws

2020

A non-target screening strategy was developed for the safety evaluation of potentially hazardous chemicals in paper food contact materials (FCMs). A tentative list of suspect analytes was generated using publicly available FCM substance inventories, the presence of contaminants in paper straws was confirmed by high-resolution Orbitrap mass spectrometry. Data-independent and data-dependent MS and MS/MS results for candidate compounds were processed using a workflow including peak detection by deconvolution, blank subtraction, retention time alignment, formula assignment and fragmentation spectra search against spectral libraries followed by

PaperFood SafetyFood contact materialsWaste managementHealth Toxicology and MutagenesisFood PackagingPublic Health Environmental and Occupational HealthFood ContaminationGeneral ChemistryGeneral MedicineToxicologyHazardous SubstancesNon targetHazardous wasteMaterials TestingEnvironmental scienceFood AnalysisFood ScienceFood Additives & Contaminants: Part A
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